4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt , 92921-24-9

Synonym(s):
SMCC, Water-Soluble;Sulfo-SMCC;Sulfosuccinimidyl- trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC;Sulfosuccinimidyl-trans-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, Sulfo-SMCC

CAS NO.：92921-24-9

Empirical Formula: C16H19N2NaO9S

Molecular Weight: 438.38

MDL number: MFCD00054978

EINECS: 618-887-3

PRODUCT Properties

• Melting point: >270°C (dec.)
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: H2O: soluble2.5mg/mL
• form: powder
• color: white to light brown
• Water Solubility: Soluble in water (2.5 mg/ml) and dimethyl formamide.
• Stability: Moisture Sensitive
• InChI: InChI=1S/C16H18N2O9S.Na.H/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26)
• InChIKey: VUFNRPJNRFOTGK-UHFFFAOYSA-M
• SMILES: O(N1C(CC(S(O)(=O)=O)C1=O)=O)C(C1CCC(CN2C(C=CC2=O)=O)CC1)=O.[NaH]

Description and Uses

Sulfo-SMCC is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi
• Risk Statements: 36/37/38-20/21-61
• Safety Statements: 26-45-53
• WGK Germany: 3
• HS Code: 29251900