Methyl 3-formyl-4-hydroxybenzoate , 97% , 24589-99-9

Synonym(s):
3-Formyl-4-hydroxybenzoes?ure-methylester;5-(Methoxycarbonyl)salicylaldehyde

CAS NO.：24589-99-9

Empirical Formula: C9H8O4

Molecular Weight: 180.16

MDL number: MFCD01661473

EINECS: 625-799-9

PRODUCT Properties

• Melting point: 80-84 °C
• Boiling point: 299.3±25.0 °C(Predicted)
• Density: 1.310±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• pka: 6.56±0.18(Predicted)
• form: solid
• color: Pale yellow
• InChI: InChI=1S/C9H8O4/c1-13-9(12)6-2-3-8(11)7(4-6)5-10/h2-5,11H,1H3
• InChIKey: ADSJCWKOKYOJSZ-UHFFFAOYSA-N
• SMILES: C(OC)(=O)C1=CC=C(O)C(C=O)=C1

Description and Uses

Methyl 3-Formyl-4-hydroxybenzoate is a useful synthetic intermediate in the synthesis of 1,2-Benzisoxazole-5-carboxylic Acid (B197900). Also a useful synthetic intermediate in the synthesis of Roflumilast (R639700); a selective phosphodiesterase 4 (PDE4) inhibitor and antiasthmatic in the treatment of chronic obstructive pulmonary disease.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38
• Safety Statements: 26
• WGK Germany: 3
• RTECS: DH1421520
• Hazard Note: Harmful
• HS Code: 29189900