Moxifloxacin HCl , ≥99% , 186826-86-8
Synonym(s):
12-8039;1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;Avalox;BAY12-8039;Moxifloxacin hydrochloride
CAS NO.：186826-86-8
Empirical Formula: C21H25ClFN3O4
Molecular Weight: 437.892
MDL number: MFCD00949117
EINECS: 641-756-7
| Pack Size | Price | Stock | Quantity |
| 50MG | RMB23.20 | In Stock |
|
| 100MG | RMB35.20 | In Stock |
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| 500MG | RMB55.20 | In Stock |
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| 1g | RMB103.20 | In Stock |
|
| 5g | RMB396.00 | In Stock |
|
| 25g | RMB1504.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | Slightly yellow to yellow crystalline powder, mp 324-325° |
| alpha | 25D -256° (c = 0.5 in water) |
| Boiling point: | 636℃ |
| RTECS | VB1983750 |
| Flash point: | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| Water Solubility | Sparingly soluble in water. Soluble in DMSO |
| BRN | 8377447 |
| InChIKey | IDIIJJHBXUESQI-DFIJPDEKSA-N |
| SMILES | N1(C2CC2)C2=C(C=C(F)C(N3C[C@]4([H])CCCN[C@]4([H])C3)=C2OC)C(=O)C(C(O)=O)=C1.[H]Cl |&1:12,18,r| |
| CAS DataBase Reference | 186826-86-8(CAS DataBase Reference) |
Description and Uses
Moxifioxacin hydrochlodde is one of the two new fluoroquinolonecarboxylic acid antibiotics introduced in 1999 for the treatment of respiratory tract infections such as community-acquired pneumonia, acute exacerbations of bronchitis or acute sinusitis. Moxifloxacin can be synthesized through a 12 step sequence from the classical 4-quinolone-3-carboxylic acid template. Some advantages of Moxifloxacin over Ciprofloxacin, another of Bayer's launched quinolones, have been shown, i.e. an enhanced activity against Gram-positive bacteria (Streptococcus pneumoniae, Clostndium pneumoniae), a favorable pharmacokinetic profile (good tissue penetration and plasma concentrations above MICs) and a lack of phototoxicity (UVA irradiation).
Moxifloxacin Hydrochloride is an antibacterial agent that inhibits the activities of Topo II (DNA gyrase) and topoisomerase IV.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H319-H412 |
| Precautionary statements | P264-P270-P273-P280-P301+P312-P305+P351+P338 |
| WGK Germany | 2 |
| HazardClass | IRRITANT |
