A5533312
1-Methylindole-2-carboxylic Acid , ≥98.0%(GC) , 16136-58-6
Synonym(s):
NSC 68357
| Pack Size | Price | Stock | Quantity |
| 1G | RMB74.40 | In Stock |
|
| 5G | RMB236.80 | In Stock |
|
| 25g | RMB861.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 212-213 °C (dec.) (lit.) |
| Boiling point: | 389.0±15.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Crystalline Powder |
| pka | 4.19±0.30(Predicted) |
| color | Beige |
| InChI | 1S/C10H9NO2/c1-11-8-5-3-2-4-7(8)6-9(11)10(12)13/h2-6H,1H3,(H,12,13) |
| InChIKey | MAHAMBLNIDMREX-UHFFFAOYSA-N |
| SMILES | Cn1c(cc2ccccc12)C(O)=O |
| CAS DataBase Reference | 16136-58-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Methylindole-2-carboxylic acid(16136-58-6) |
Description and Uses
- Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
- Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions
- Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes
- Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation
- Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
- Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| RTECS | NL6012400 |
| HazardClass | IRRITANT |
| HS Code | 29339980 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
