Methyl D-(+)-Lactate , ≥98.0%(GC) , 17392-83-5

Synonym(s):
D-Lactic acid methyl ester;Methyl (R)-(+)-lactate

CAS NO.：17392-83-5

Empirical Formula: C4H8O3

Molecular Weight: 104.1

MDL number: MFCD00004517

EINECS: 241-420-6

PRODUCT Properties

• alpha: 8.5 º (c=neat)
• Boiling point: 144-145 °C(lit.)
• Density: 1.09 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.413(lit.)
• Flash point: 121 °F
• storage temp.: Inert atmosphere,2-8°C
• solubility: Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
• form: Liquid
• pka: 13.07±0.20(Predicted)
• color: Clear colorless
• optical activity: [α]21/D +8.4°, neat
• Water Solubility: miscible, hydrolyses
• Merck: 14,6094
• InChIKey: LPEKGGXMPWTOCB-GSVOUGTGSA-N
• LogP: -0.719 (est)
• CAS DataBase Reference: 17392-83-5(CAS DataBase Reference)

Description and Uses

(+)-Methyl D-lactate can be used as a starting material in the asymmetric preparation of:

• Neomethymycin, a macrolide which contains 12-membered macrolactone that is used as a potent biological agent.
• PM-toxin A.

It can also be used as a chiral pool along with D-(-)-tartaric acid in the stereoselective total synthesis of separacenes A and B via Trost-Rychnovsky alkyne rearrangement, Horner-Wadsworth-Emmons olefination as well as Corey-Bakshi-Shibata reaction.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Warning
• Hazard statements: H226-H319-H335
• Precautionary statements: P210-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 10-36/37
• Safety Statements: 16-24-24/25
• RIDADR: UN 3272 3/PG 3
• WGK Germany: 1
• HazardClass: 3
• PackingGroup: III
• HS Code: 29181100
• Limited Quantities: 5.0 L (1.3 gallons) (liquid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)