5-Methylisatin , ≥98.0% , 608-05-9

Synonym(s):
5-Methylindole-2,3-dione;NSC 9398

CAS NO.：608-05-9

Empirical Formula: C9H7NO2

Molecular Weight: 161.16

MDL number: MFCD00005721

EINECS: 210-152-1

PRODUCT Properties

• Melting point: 180 °C (dec.) (lit.)
• Density: 1.301±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• solubility: methanol: soluble25mg/mL, clear to slightly hazy, orange to red
• pka: 10.42±0.20(Predicted)
• form: crystalline
• color: orange
• BRN: 123738
• InChI: InChI=1S/C9H7NO2/c1-5-2-3-7-6(4-5)8(11)9(12)10-7/h2-4H,1H3,(H,10,11,12)
• InChIKey: VAJCSPZKMVQIAP-UHFFFAOYSA-N
• SMILES: N1C2=C(C=C(C)C=C2)C(=O)C1=O
• CAS DataBase Reference: 608-05-9(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-2,3-indolinedione(608-05-9)

Description and Uses

Reactant for preparation of:• ;Antimycobacterial agents1• ;Promoters of central nervous system (CNS) depression in mice2• ;Inhibitors of TAK1 kinase3• ;Anti-human immunodeficiency virus (HIV) agent4• ;Potent herpes simplex virus (HSV) inhibitors5• ;Antimicrobial agents6• ;IKKβ inhibitors7• ;Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection8• ;Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors9• ;Antibacterial and anticancer agents

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H332-H335
• Precautionary statements: P261-P280-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• RTECS: NL7939300
• HazardClass: IRRITANT
• HS Code: 29337900