Methyl Thiocyanate , 98% , 556-64-9
Synonym(s):
Thiocyanic acid methyl ester
CAS NO.：556-64-9
Empirical Formula: C2H3NS
Molecular Weight: 73.12
MDL number: MFCD00001830
EINECS: 209-134-6
PRODUCT Properties
| Melting point: | -5 °C |
| Boiling point: | 131 °C |
| Density | 1.08 |
| refractive index | 1.467-1.469 |
| Flash point: | 38 °C |
| storage temp. | Poison room |
| Water Solubility | Practically insoluble in water |
| solubility | Chloroform (Soluble), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless to light yellow |
| Odor | at 0.01?%?in?propylene glycol. sulfury onion |
| Sensitive | Moisture Sensitive |
| Merck | 14,6127 |
| Dielectric constant | 4.3（19℃） |
| LogP | 0.502 (est) |
| CAS DataBase Reference | 556-64-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Thiocyanic acid, methyl ester(556-64-9) |
| EPA Substance Registry System | Methyl thiocyanate (556-64-9) |
Description and Uses
Methyl thiocyanate is a colorless liquid withan onion-like odor. Molecular weight = 73.12; Boilingpoint= 130-133℃; Freezing/Melting point= - 51℃.Very slightly soluble in water.
Methyl thiocyanate is a reagent that is used in the synthesis of WAK 4103 (W498200), which is a metabolite of Imidacloprid (I274990), a neonicotinoid; the active ingredient in certain neuro-active insecticides. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens.Nauen, R., et. al.: Pestic. Sci., 55, 265 (1999); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009); Patial, A., et al.: Env. Ecol., 27, 320 (2009); Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009); Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009); Chem. and Eng. News 90: 10 (2012)
Safety
| Symbol(GHS) |   GHS02,GHS06 |
| Signal word | Danger |
| Hazard statements | H226-H301+H311+H331-H319-H335 |
| Precautionary statements | P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 23/24/25-10-36/37 |
| Safety Statements | 28A-27-26-16-45-36/37/39 |
| RIDADR | UN1992 |
| WGK Germany | 3 |
| RTECS | XL1575000 |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29309099 |
| Hazardous Substances Data | 556-64-9(Hazardous Substances Data) |
| Toxicity | LD50 i.p. in mice: 315 nmoles/g (Ohkawa) |
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) |
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) |
