A6147312
3-Nitrophenol , standardforGC,>99%(GC) , 554-84-7
Synonym(s):
m-Nitrophenol;m-NP;3-Nitrophenol;3-NP;m-Nitrophenol
CAS NO.：554-84-7
Empirical Formula: C6H5NO3
Molecular Weight: 139.11
MDL number: MFCD00007240
EINECS: 209-073-5
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 96-98 °C (lit.) |
| Boiling point: | 194 °C/70 mmHg (lit.) |
| bulk density | 640kg/m3 |
| Density | 1,49 g/cm3 |
| refractive index | 1.5723 (estimate) |
| Flash point: | 102°C |
| storage temp. | Store at +5°C to +30°C. |
| solubility | 13.5g/l insoluble |
| pka | 8.28(at 25℃) |
| form | Crystalline Powder |
| color | Yellow to brown |
| PH | 6.6-8.6 (H2O, 20℃) |
| PH Range | 6.6(colourless)-8.6(yellow/orange) |
| Water Solubility | 13.5 g/L (25 ºC) |
| λmax | 570nm |
| Merck | 14,6618 |
| BRN | 1907946 |
| Major Application | Display device, semiconductor device, sensors, high voltage capacitors, energetic materials, electrolyte batteries, inks, correction fluid, detergent, leak detection method, lubricants, insecticide, food storage, inhibition of amyloidoses, detect bacterialinfection, drugs, material for evaluating dental caries activity |
| Cosmetics Ingredients Functions | HAIR DYEING |
| InChI | 1S/C6H5NO3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8H |
| InChIKey | RTZZCYNQPHTPPL-UHFFFAOYSA-N |
| SMILES | Oc1cccc(c1)[N+]([O-])=O |
| CAS DataBase Reference | 554-84-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 3-nitro-(554-84-7) |
| EPA Substance Registry System | m-Nitrophenol (554-84-7) |
Description and Uses
3-Nitrophenol is a chemical reagent used in various organic syntheses. Used in the synthesis of RAGE inhibitors via the etherification of phenols. Also used in the synthesis of kinase inhibitors against epidermal growth factor receptor T790M mutation.
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302-H315-H318 |
| Precautionary statements | P280-P305+P351+P338 |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-38-41-36/37/38-33-20/21/22 |
| Safety Statements | 26-36/37-45-36/37/39-22-28 |
| RIDADR | UN 1663 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | SM1925000 |
| F | 8 |
| Autoignition Temperature | 400 °C |
| Hazard Note | Harmful/Irritant |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29089000 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 |
| Hazardous Substances Data | 554-84-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in mice, rats: 1414, 933 mg/kg, K. C. Back et al., Reclassification of Materials Listed as Transportation Health Hazards (TSA-20-72-3; PB214-270, 1972) |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
