A6213912
Nutlin-3 , ≥97% , 890090-75-2
CAS NO.：890090-75-2
Empirical Formula: C30H30Cl2N4O4
Molecular Weight: 581.49
MDL number: MFCD07784509
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB411.12 | In Stock |
|
| 10MG | RMB529.60 | In Stock |
|
| 50MG | RMB1908.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.36 |
| storage temp. | Store at -20°C |
| solubility | ≥58.2 mg/mL in DMSO; insoluble in H2O; ≥5.69 mg/mL in EtOH with ultrasonic |
| form | solid |
| pka | 14.35±0.20(Predicted) |
Description and Uses
(Rac)-Nutlin-3 (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). (Rac)-Nutlin-3 inhibits MDM2-p53?interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. (Rac)-Nutlin-3 has the potential for the study of TP53?wild-type ovarian carcinomas[1][2].
Safety
| HS Code | 29339900 |
