1-Pyrenebutyric acid N-hydroxysuccinimide ester , 95% , 114932-60-4

CAS NO.：114932-60-4

Empirical Formula: C24H19NO4

Molecular Weight: 385.41

MDL number: MFCD00077403

PRODUCT Properties

• Melting point: 132-136 °C(lit.)
• storage temp.: room temp
• solubility: Soluble in chloroform, N,N- dimethylformamide, dimethyl sulfoxide, methanol
• form: A solid
• color: Yellow solid
• Appearance: off-white solid
• λmax: 340nm, 325nm (MeOH)
• Major Application: Carbon nanotubes (single-wall carbon nanotubes (SWCNT) and multi-wall carbon nanotubes (MWCNTs)); cellulose materials for bulky paper sheets; graphene-based polymer nanocomposites materials/films; photonic materials;photovoltaic devices; polyaniline systems;poly(dimethylsiloxane) (PDMS) oligomers;poly(propylene imine) dendrimers; thin-films
• Biological Applications: Characterizing cyclodextrin-based polyrotaxanes; detecting nucleic acids,polyamines;immobilizing proteins;probing lysozyme in human serum; as a substrate for measuring polymerases activity, recombinases activity, topoisomerases activity
• InChI: InChI=1S/C24H19NO4/c26-20-13-14-21(27)25(20)29-22(28)6-2-3-15-7-8-18-10-9-16-4-1-5-17-11-12-19(15)24(18)23(16)17/h1,4-5,7-12H,2-3,6,13-14H2
• InChIKey: YBNMDCCMCLUHBL-UHFFFAOYSA-N
• SMILES: C1(CCCC(ON2C(=O)CCC2=O)=O)=C2C3=C4C(C=C2)=CC=CC4=CC=C3C=C1

Description and Uses

Pyrene is a polyaromatic hydrocarbon which exhibits fluorescence in blue range of the spectrum. When two pyrene residues are closely spaced, excimer fluorescence is observed at longer wavelength. Therefore, pyrene is useful as a proximity label.

Pyrene exhibits affinity to graphite, and can be used as an anchor group for graphite. This reagent can be conjugated with biomolecules for their subsequent immobilization on graphite surfaces.

This NHS ester allows to label biomolecules with amino groups, such as proteins, peptides, amino-DNA and other molecules.

Pyrene is also a FRET donor for perylene.

N-Hydroxysuccinimidyl Pyrenebutanoate is a novel fluorescent monomer used as new material for protein conjugation. Dyes and metabolites.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 2928.00.5000