Isoxazole-4-boronic acid pinacol ester , ≥95% , 928664-98-6

CAS NO.：928664-98-6

Empirical Formula: C9H14BNO3

Molecular Weight: 195.02

MDL number: MFCD06657891

PRODUCT Properties

• Melting point: 110-115℃
• Boiling point: 289.9±13.0 °C(Predicted)
• Density: 1.08±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• form: solid
• pka: -2.02±0.50(Predicted)
• color: White to off-white
• InChI: InChI=1S/C9H14BNO3/c1-8(2)9(3,4)14-10(13-8)7-5-11-12-6-7/h5-6H,1-4H3
• InChIKey: LXCICYRNWIGDQA-UHFFFAOYSA-N
• SMILES: O1C=C(B2OC(C)(C)C(C)(C)O2)C=N1

Description and Uses

4-?Isoxazoleboronic Acid Pinacol Ester is a reagent used in the preparation of potent and selective in vivo probe (GNE-272) for bromodomains of CBP/EP300 involved in cancer and immune system regulation.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H312+H332
• Precautionary statements: P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
• Hazard Codes: Xn
• Risk Statements: 20/21/22
• WGK Germany: 3
• HS Code: 29349990