Nervonic acid , ≥95.0%(GC) , 506-37-6
Synonym(s):
cis-15-Tetracosenoic acid;Selacholeic acid
CAS NO.：506-37-6
Empirical Formula: C24H46O2
Molecular Weight: 366.62
MDL number: MFCD00010507
EINECS: 610-549-3
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB559.20 | In Stock |
|
| 1G | RMB1136.00 | In Stock |
|
| 5g | RMB3679.20 | In Stock |
|
| 10g | RMB5847.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 42-43 °C (lit.) |
| Boiling point: | 459.84°C (rough estimate) |
| Density | 0.9009 (rough estimate) |
| refractive index | 1.4806 (estimate) |
| Flash point: | >230 °F |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Hexanes (Very Slightly) |
| pka | 4.78±0.10(Predicted) |
| form | Liquid |
| color | White to Pale Yellow |
| biological source | plant |
| BRN | 1728551 |
| InChI | InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9- |
| InChIKey | GWHCXVQVJPWHRF-KTKRTIGZSA-N |
| SMILES | C(O)(=O)CCCCCCCCCCCCC/C=C\CCCCCCCC |
| LogP | 10.890 (est) |
| CAS DataBase Reference | 506-37-6(CAS DataBase Reference) |
Description and Uses
Nervonic acid, also known as shark oil acid, is a monounsaturated omega-9 fatty acid that exists in nerve tissue and fish oil. It was first discovered in shark brain and is a component of cerebroside, the main source of in shark brain and shark oil. It is also found in the sphingolipids of white matter in human brain.
Nervonic acid is a bioactive substance possessing multiple physiological functions. It can repair nerve cell damage caused by oxidative stress and alleviate motor impairments in mice with Parkinson's disease. Increasing dietary nervonic acid also improves metabolic parameters and limits weight gain in mice fed a high-fat diet [1]. Furthermore, faecal nervonic acid serves as a biomarker for diagnosing and monitoring inflammatory bowel disease [2].
[1] LAURA J. W. KEPPLEY. Nervonic acid limits weight gain in a mouse model of diet-induced obesity[J]. The FASEB Journal, 2020, 34 11: 15314-15326. DOI:10.1096/fj.202000525R.
[2] CLAUDIA KUNST. Fecal Nervonic Acid as a Biomarker for Diagnosing and Monitoring Inflammatory Bowel Disease.[J]. Biomedicines, 2024, 12 12. DOI:10.3390/biomedicines12122764.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 8-10 |
| HS Code | 2916.19.3000 |
| Storage Class | 11 - Combustible Solids |
