<i>N</i>-Succinimidyl 3-Maleimidobenzoate [Cross-linking Reagent] , >98.0%(HPLC) , 58626-38-3

Synonym(s):
MBS

CAS NO.：58626-38-3

Empirical Formula: C15H10N2O6

Molecular Weight: 314.25

MDL number: MFCD00005514

EINECS: 261-368-8

PRODUCT Properties

• Melting point: 175-177 °C(lit.)
• Boiling point: 524.5±52.0 °C(Predicted)
• Density: 1.59±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: ethyl acetate or DMF: ≤20 mg/mL may require addition of solvent to coupling buffer to at least 5% to maintain solubility
• form: crystalline
• pka: -2.63±0.20(Predicted)
• color: White to Almost white
• Sensitive: Moisture & Light Sensitive
• BRN: 1505254
• InChIKey: LLXVXPPXELIDGQ-UHFFFAOYSA-N
• CAS DataBase Reference: 58626-38-3(CAS DataBase Reference)

Description and Uses

MBS is a heterobifunction crosslinker that contains a maleimide group which is reactive towards sulfhydryls and an NHS ester, useful for targeting amine groups.

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is a heterobifunctional coupling reagent useful for forming enzyme immunoconjugates. The reactive groups are the NHS ester and maeimide.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• HS Code: 29280000