Ozagrel hydrochloride hydrate , ≥98%(HPLC) , 78712-43-3
Synonym(s):
(E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate;OKY-046
CAS NO.：78712-43-3
Empirical Formula: C13H13ClN2O2
Molecular Weight: 264.71
MDL number: MFCD06795644
EINECS: 928-470-0
| Pack Size | Price | Stock | Quantity |
| 1G | RMB164.00 | In Stock |
|
| 5G | RMB186.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 214-217° |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | H2O: soluble |
| form | solid |
| color | white to off-white |
| Water Solubility | H2O: soluble |
| Merck | 14,6980 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month. |
| CAS DataBase Reference | 78712-43-3(CAS DataBase Reference) |
Description and Uses
Ozagrel HCl (78712-43-3) is a potent and selective inhibitor of thromboxane A2 (TXA2) synthetase (IC50 = 4 nM). It does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase, or PGE2 isomerase (IC50 > 1 mM)[1]. Ozagrel HCl inhibits platelet aggregation in vitro[2] and arachidonate-induced arterial contraction in vivo. It protects against arachidonate-induced sudden death in rabbits[3] and alleviates liver injury induced by acetaminophen overdose in mice[4].
Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
| RIDADR | 3077 |
| WGK Germany | 2 |
| RTECS | UD3380000 |
| HS Code | 29332900 |
