α-Methyl-L-phenylalanine , 98% , 23239-35-2

Synonym(s):
α-Me-Phe-OH;(S)-(−)-2-Amino-2-methyl-3-phenylpropionic acid

CAS NO.：23239-35-2

Empirical Formula: C10H13NO2

Molecular Weight: 179.22

MDL number: MFCD00145244

EINECS: 200-528-9

PRODUCT Properties

• Melting point: 244-246 °C
• alpha: 2.4 º (c=1, 6N HCl)
• Boiling point: 312.8±30.0 °C(Predicted)
• Density: 1.166±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Aqueous Acid (Slightly), Water (Slightly)
• pka: 2.25±0.10(Predicted)
• form: Fine Crystalline Powder
• color: White
• Water Solubility: soluble
• BRN: 4668990
• Major Application: peptide synthesis
• InChI: 1S/C10H13NO2/c1-10(11,9(12)13)7-8-5-3-2-4-6-8/h2-6H,7,11H2,1H3,(H,12,13)/t10-/m0/s1
• InChIKey: HYOWVAAEQCNGLE-JTQLQIEISA-N
• SMILES: C[C@](N)(Cc1ccccc1)C(O)=O
• CAS DataBase Reference: 23239-35-2(CAS DataBase Reference)

Description and Uses

a-Methyl-L-phenylalanine is used to prepare hippuryl-a-methylphenylalanine and hippuryl-a-methylphenyllactic acid as substrates for carboxypeptidase A. It is also used in the synthesis of high affinity tachykinin NK2 receptor antagonists.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P280-P305+P351+P338
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 24/25
• WGK Germany: 3
• Storage Class: 13 - Non Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral