A6797812
Pracinostat (SB939) , ≥98% , 929016-96-6
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB672.80 | In Stock |
|
| 10MG | RMB1124.80 | In Stock |
|
| 50MG | RMB3494.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.11 |
| storage temp. | Store at -20°C |
| solubility | insoluble in H2O; ≥11.4 mg/mL in DMSO; ≥24.8 mg/mL in EtOH with ultrasonic |
| form | solid |
| pka | 8.67±0.23(Predicted) |
| color | White to light brown |
| InChI | InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+ |
| InChIKey | JHDKZFFAIZKUCU-ZRDIBKRKSA-N |
| SMILES | C(NO)(=O)/C=C/C1=CC=C2N(CCN(CC)CC)C(CCCC)=NC2=C1 |
Description and Uses
Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use in patients with advanced solid malignancies. Potent Histone deacetylase inhibitor.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 |
