Proparacaine HCl , ≥99% , 5875-06-9

Synonym(s):
Proxymetacaine hydrochloride

CAS NO.：5875-06-9

Empirical Formula: C16H27ClN2O3

Molecular Weight: 330.85

MDL number: MFCD00083467

EINECS: 227-541-7

PRODUCT Properties

• Melting point: 182.0-183.3°
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), Methanol, Water
• form: Solid
• pka: 3.2(at 25℃)
• color: White to Off-White
• λmax: 300nm(MeOH)(lit.)
• Merck: 14,7807
• InChI: InChI=1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H
• InChIKey: BFUUJUGQJUTPAF-UHFFFAOYSA-N
• SMILES: C(OCCN(CC)CC)(=O)C1=CC=C(OCCC)C(N)=C1.[H]Cl
• CAS DataBase Reference: 5875-06-9(CAS DataBase Reference)

Description and Uses

Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.

Topical anesthetic (ophthalmic); Neuronal conductance inhibitor.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H312+H332-H317-H319
• Precautionary statements: P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36-43
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: DG3065000
• HS Code: 2922504500