2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride , >98.0%(HPLC) , 70918-74-0

Synonym(s):
N-(1,4-Benzodioxane-2-carbonyl)piperazine

CAS NO.：70918-74-0

Empirical Formula: C13H17ClN2O3

Molecular Weight: 284.74

MDL number: MFCD00729051

EINECS: 415-660-9

PRODUCT Properties

• Melting point: 105-108°C
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: powder to crystal
• color: White to Almost white
• Stability: Hygroscopic
• InChI: InChI=1S/C13H16N2O3.ClH/c16-13(15-7-5-14-6-8-15)12-9-17-10-3-1-2-4-11(10)18-12;/h1-4,12,14H,5-9H2;1H
• InChIKey: TUKBWYXLYINULI-UHFFFAOYSA-N
• SMILES: C12=CC=CC=C1OCC(C(=O)N1CCNCC1)O2.Cl
• CAS DataBase Reference: 70918-74-0(CAS DataBase Reference)

Description and Uses

1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride (Doxazosin EP Impurity B) is an impurity of Doxazosin (D537500), a selective a1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.

Safety

• Symbol(GHS): GHS06,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H301+H311+H331-H373-H411
• Precautionary statements: P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314
• Hazard Codes: T;N,Xi,N,T
• Risk Statements: 23/24/25-48/22-51/53
• Safety Statements: 45-53-61
• RIDADR: UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all
• Hazard Note: Irritant
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 2934990002