PRODUCT Properties
| Melting point: | 213-215°C |
| alpha | D +109° (chloroform) |
| Boiling point: | 532.3±50.0 °C(Predicted) |
| Density | 376.46 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.98±0.10(Predicted) |
| color | White to Off-White |
| InChIKey | VWVSBHGCDBMOOT-SDKBDWEQNA-N |
| SMILES | [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@]1(C)[C@H]([C@H](C)C[C@@]21[H])C(=O)CO |&1:0,10,12,14,17,19,20,23,r| |
| CAS DataBase Reference | 382-67-2(CAS DataBase Reference) |
Description and Uses
Desoximetasone is a glucocorticoid.1 In vivo, desoximetasone (0.001-0.1 mg) reverses increases in epidermal cell proliferation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in SENCAR mice when administered topically. It also reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice, indicating anti-inflammatory action. Formulations containing desoximetasone have been used in the treatment of psoriasis and atopic dermatitis.WARNING This product is not for human or veterinary use.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H302-H312-H315-H317-H319-H332-H335-H351 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38-40-43 |
| Safety Statements | 22-26-36 |
| WGK Germany | 3 |
| RTECS | TU3834000 |
| HS Code | 29147000 |
