Psoralidin , 98%(HPLC) , 18642-23-4

Synonym(s):
3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one;3,9-Dihydroxy-2-prenylcoumestan

CAS NO.：18642-23-4

Empirical Formula: C20H16O5

Molecular Weight: 336.34

MDL number: MFCD10566617

PRODUCT Properties

• Melting point: 290-292°
• Boiling point: 458.8±34.0 °C(Predicted)
• Density: 1.383±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• solubility: DMSO: soluble5mg/mL, clear (warmed)
• form: powder
• pka: 8.70±0.20(Predicted)
• color: white to beige
• InChI: 1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3,5-9,21-22H,4H2,1-2H3
• InChIKey: YABIJLLNNFURIJ-UHFFFAOYSA-N
• SMILES: CC(C)=CCC1=C(C=C(OC2=O)C(C(OC3=C4)=C2C3=CC=C4O)=C1)O

Description and Uses

Psoralidin is a furanocoumarin isolated from the seeds of P. corylifolia, a medicinal plant found in southeastern Asia, that has been shown to induce cytotoxicity against various cancer cells. Through TNF-related apoptosis-inducing ligand-mediated events, psoralidin at 50 μM can induce the death of HeLa cancer cells. It also can induce apoptosis of androgen-dependent (LNCaP, C4-2B) and androgen-independent (DU-145, PC-3) prostate cancer cells and inhibit the growth of PC-3 xenograft tumors in nude mice.

Psoralidin is an antibacterial and antioxidant reagent.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• WGK Germany: 3
• HS Code: 2932.20.4500
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral