Atropine , 10mMinDMSO , 51-55-8

Synonym(s):
Atropine;Atropine solution;endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester;Hyoscyamine;Tropine tropate

CAS NO.：51-55-8

Empirical Formula: C17H23NO3

Molecular Weight: 289.37

MDL number: MFCD00022622

EINECS: 200-104-8

Pack Size	Price	Stock	Quantity
1ml	RMB559.20	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Melting point:	115-118 °C
Boiling point:	431.53°C (rough estimate)
Density	1.0470 (rough estimate)
refractive index	1.5200 (estimate)
Flash point:	2℃
storage temp.	-20°C
solubility	H₂O: 2 mg/mL
form	powder
pka	9.7(at 21℃)
color	white
Water Solubility	1.6g/L(18 ºC)
Sensitive	Light Sensitive
Merck	14,875
BRN	91260
InChIKey	RKUNBYITZUJHSG-SPUOUPEWSA-N
CAS DataBase Reference	51-55-8(CAS DataBase Reference)
NIST Chemistry Reference	Atropine(51-55-8)
EPA Substance Registry System	Atropine (51-55-8)

Description and Uses

Atropine is a naturally occurring tropane alkaloid extracted from plants of the family Solanaceae including deadly nightshade (A. belladonna). It is a non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M₁, M₂, M₃, M₄, and M₅ (pKBs range from 8.9-9.8). Atropine increases firing of the sinoatrial node and conduction through the atrioventricular node of the heart, opposes the actions of the vagus nerve, blocks acetylcholine receptor sites, and decreases bronchial secretions. It is classified as an anticholinergic (parasympatholytic) drug and commonly used to dilate the pupils, increase heart rate, reduce salivation and other secretions, and as an antidote against organophosphate poisoning.

Scopolamine is found in the leaves of Daturametel L., D. meteloides L., and D. fastuosavar. alba (Cordell 1978). It is used as asedative, a preanesthetic agent, and in thetreatment of motion sickness (Merck 1989).

Safety

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H300+H330
Precautionary statements	P260-P264-P270-P271-P284-P304+P340+P310
Hazard Codes	T+,Xn,F
Risk Statements	26/28-36/37/38-20/21/22-36-11
Safety Statements	25-45-36-26-36/37-16
RIDADR	1544
WGK Germany	3
RTECS	CK0700000
F	8-10-23
TSCA	Yes
HazardClass	6.1
PackingGroup	III
HS Code	29399900
Hazardous Substances Data	51-55-8(Hazardous Substances Data)
Toxicity	LD50 orally in rats: 750 mg/kg (Cahen, Tvede)