(-)-CoreyLactone , 10mMinDMSO , 32233-40-2

Synonym(s):
(−)-Corey lactone

CAS NO.：32233-40-2

Empirical Formula: C8H12O4

Molecular Weight: 172.18

MDL number: MFCD00075234

EINECS: 608-721-8

PRODUCT Properties

• Melting point: 117-119 °C(lit.)
• Boiling point: 262.49°C (rough estimate)
• Density: 1.2104 (rough estimate)
• refractive index: 1.4455 (estimate)
• storage temp.: Sealed in dry,Room Temperature
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 14.36±0.40(Predicted)
• form: Crystalline Powder or Crystals
• color: White to beige-brown
• optical activity: [α]20/D 44°, c = 1.4 in methanol
• InChI: InChI=1S/C8H12O4/c9-3-5-4-1-8(11)12-7(4)2-6(5)10/h4-7,9-10H,1-3H2/t4-,5-,6-,7+/m1/s1
• InChIKey: VYTZWRCSPHQSFX-GBNDHIKLSA-N
• SMILES: O1C(=O)C[C@]2([H])[C@@H](CO)[C@H](O)C[C@]12[H]
• CAS DataBase Reference: 32233-40-2(CAS DataBase Reference)

Description and Uses

(-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 24/25
• WGK Germany: 3
• HS Code: 29322090