A7001858
CeftriaxoneSodiumTrihydrate , 10mMinWater , 104376-79-6
CAS NO.：104376-79-6
Empirical Formula: C18H16N8Na2O7S3.31/2H2O
Molecular Weight: 598.54
MDL number: MFCD01750405
EINECS: 626-956-4
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 236 °C |
| alpha | D25 -165° (c = 1 in water) (calc for water-free substance) |
| refractive index | -160 ° (C=1, H2O) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | H2O: soluble50mg/mL |
| pka | ~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH) |
| form | powder or crystals |
| color | White to Off-White |
| Water Solubility | Freely soluble in water |
| InChIKey | FDRNWTJTHBSPMW-BBJOQENWSA-L |
| SMILES | C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NC(=O)C(=O)NN1C)(=O)O.[NaH].O |&1:5,7,r| |
Description and Uses
Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.
An antibacterial, a third-generation cephalosporin.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315-H317-H319-H334-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42/43 |
| Safety Statements | 26-36-45-37-24-22 |
| WGK Germany | 1 |
| RTECS | XI0368800 |
| HS Code | 29349990 |
| Toxicity | LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman) |
