A7011858
Ansamitocinp-3(Maytansinolisobutyrate,NSC292222) , 10mMinDMSO , 66584-72-3
CAS NO.：66584-72-3
Empirical Formula: C32H43ClN2O9
Molecular Weight: 635.14
MDL number: MFCD00274586
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB516.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 190-192℃ |
| Boiling point: | 833.1±65.0 °C(Predicted) |
| Density | 1.29 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: 100 mg/mL (157.45 mM);Ethanol: 55 mg/mL (86.60 mM) |
| pka | 9.82±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Water: Insoluble |
| InChIKey | OPQNCARIZFLNLF-VLSFGAMINA-N |
Description and Uses
Ansamitocin P 3 is a macrocyclic antitumor antibiotic that works by depolymerizing microtubules in both interphase and mitosis, and perturbs chromosome segregation.
Ansamitocin P-3 is an antitumor agent that binds to cell division protein FtsZ in Actinosynnema pretiosum.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302+H332-H315-H319-H335 |
| Precautionary statements | P261-P264-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 20/22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | OQ2293000 |
| HS Code | 2941900000 |
