Benzamidinehydrochloride , 10mMinDMSO , 1670-14-0
Synonym(s):
Additive Screening Solution 37/Kit-No 78374;Benzamidine hydrochloride solution;Benzamidine, Hydrochloride - CAS 1670-14-0 - Calbiochem
CAS NO.：1670-14-0
Empirical Formula: C7H9ClN2
Molecular Weight: 156.61
MDL number: MFCD00013025
EINECS: 216-795-4
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 86-88 °C(lit.) |
| storage temp. | 2-8°C |
| solubility | DMF: 25 mg/ml DMSO: 25 mg/ml Ethanol: 10 mg/ml PBS (pH 7.2): 3 mg/ml |
| form | Powder |
| color | White to off-white |
| PH | 4.0 to 6.5(50g/L, 25 ℃) |
| Water Solubility | soluble |
| BRN | 3594959 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily |
| InChI | InChI=1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H |
| InChIKey | LZCZIHQBSCVGRD-UHFFFAOYSA-N |
| SMILES | C1(C(=N)N)=CC=CC=C1.Cl |
| CAS DataBase Reference | 1670-14-0(CAS DataBase Reference) |
| EPA Substance Registry System | Benzenecarboximidamide, monohydrochloride (1670-14-0) |
Description and Uses
Benzamidine hydrochloride is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.
In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.
Benzamidine is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Kis = 35, 350, and 220 μM, respectively). In addition to its use as a general serine protease inhibitor, benzamidine is used, when immobilized, to purify novel proteases.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39-36 |
| WGK Germany | 3 |
| RTECS | CV6260000 |
| F | 3-21 |
| HS Code | 29252900 |
