A7070758
DelaprilHydrochloride , 10mMinDMSO , 83435-67-0
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 166-170℃ |
| alpha | D22 +18.5° (c = 1 in methanol) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO:174.0(Max Conc. mg/mL);355.82(Max Conc. mM) |
| form | Solid |
| color | White to off-white |
| InChIKey | FDJCVHVKXFIEPJ-YSHIOSSBNA-N |
| SMILES | C1(CC2C=CC=CC=2C1)N(CC(=O)O)C(=O)[C@H](C)N[C@H](C(=O)OCC)CCC1=CC=CC=C1.Cl |&1:16,19,r| |
| CAS DataBase Reference | 83435-67-0(CAS DataBase Reference) |
Description and Uses
Delapril is a new angiotensin-converting enzyme (ACE) inhibitor useful in the treatment of essential hypertension. Orally administered delapril is a prodrug which is de-esterified to its active diacid metabolite. In hypertensive patients delapril significantly decreased systolic blood pressure and ACE activity 24 hours after dosing without affecting endogeneous creatinine clearance.
Antihypertensive; enzyme inhibitor (angiotensinconverting).
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P280-P305+P351+P338 |
| RTECS | MB9668000 |
