(R,R)-(-)-N,N′-Dimethyl-1,2-cyclohexanediamine , ≥97.0%(GC) , 68737-65-5

Synonym(s):
(R,R)-(−)-N,N′-Dimethyl-1,2-diaminocyclohexane;trans-1,2-Bis(methylamino)cyclohexane

CAS NO.：68737-65-5

Empirical Formula: C8H18N2

Molecular Weight: 142.24

MDL number: MFCD00671527

PRODUCT Properties

• Melting point: 39-44 °C
• alpha: -145 º (c=4.47 in chloroform)
• Boiling point: 249.85°C (rough estimate)
• Density: 0.902
• refractive index: -140 ° (C=4, CHCl3)
• Flash point: 74 °C
• storage temp.: 2-8°C
• pka: 11.04±0.40(Predicted)
• form: Low Melting Solid
• color: White to light yellow
• optical activity: [α]/D -145±5°, c = 4.47 in chloroform
• InChI: InChI=1S/C8H18N2/c1-9-7-5-3-4-6-8(7)10-2/h7-10H,3-6H2,1-2H3/t7-,8-/m1/s1
• InChIKey: JRHPOFJADXHYBR-HTQZYQBOSA-N
• SMILES: [C@@H]1(NC)CCCC[C@H]1NC
• CAS DataBase Reference: 68737-65-5(CAS DataBase Reference)

Description and Uses

(R,R)-(?)-N,N′-Dimethyl-1,2-cyclohexanediamine can be used:

• As a ligand in the preparation of 4H-benzo[f]imidazo[1,4]diazepin-6-one through multi-component Ullmann coupling reaction.
• In one of the key synthetic steps for the preparation of tricyclic γ-secretase modulators.
• To prepare chiral fluorous diamino-diol proligand, which is used in the synthesis of zirconium metal complexes applicable as catalysts in 1-hexene polymerization.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H314
• Precautionary statements: P270-P280-P301+P312-P301+P330+P331-P303+P361+P353-P305+P351+P338
• Hazard Codes: C
• Risk Statements: 34-22
• Safety Statements: 45-36/37/39-25-26
• RIDADR: 3259
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: Ⅱ
• HS Code: 29213000
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)