Rocuronium Bromide , ≥98% , 119302-91-9

Synonym(s):
Rocuronium bromide

CAS NO.：119302-91-9

Empirical Formula: C32H53BrN2O4

Molecular Weight: 609.68

MDL number: MFCD00867768

EINECS: 601-597-6

PRODUCT Properties

• Melting point: 162-1640C
• alpha: D20 +18.7° (c = 1.03 in CHCl3)
• storage temp.: Inert atmosphere,2-8°C
• solubility: H2O: soluble100mg/mL, clear, light yellow
• form: Powder to Crystal
• color: White to Yellow
• Water Solubility: H2O: 100mg/mL, clear, light yellow
• Merck: 14,8246
• Stability: Hygroscopic
• InChIKey: OYTJKRAYGYRUJK-FMCCZJBLSA-M
• CAS DataBase Reference: 119302-91-9(CAS DataBase Reference)

Description and Uses

Rocuronium bromide is a short-acting nondepolarizing steroidal neuromuscular blocker introduced in the U.S.A as Zemuron and in the United Kingdom as Esmeron. k is indicated for use as an adjunct to general anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Rocuroniurn bromide has a significantly more rapid onset than other intermediate acting neuromuscular blockers, comparable to succinylcholine but with a very stable cardiovascular profile and has an improved side effect profile. It has been reported that good to excellent intubation conditions were achieved only one minute after a bolus dose of 600μg/kg of rocuronium bromide. It has a short duration of action, therefore, is useful for rapid sequence intubation without unacceptable delays in the spontaneous recovery of neuromuscular function.

A non-depolarizing neuromuscular blocker used in anesthesia to help insert breathing tubes.

Safety

• Symbol(GHS): GHS07,GHS06
• Signal word: Danger
• Hazard statements: H331-H312-H302-H330
• Precautionary statements: P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P280-P302+P352-P312-P322-P363-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P312-P330-P501
• WGK Germany: 3
• HS Code: 2934990002