Salicylic acid , AR,99.5% , 69-72-7
Synonym(s):
2-Hydroxybenzoic acid;Acidum salicylicum;Salicylic Acid
CAS NO.：69-72-7
Empirical Formula: C7H6O3
Molecular Weight: 138.12
MDL number: MFCD00002439
EINECS: 200-712-3
| Pack Size | Price | Stock | Quantity |
| 250G | RMB55.20 | In Stock |
|
| 1KG | RMB159.20 | In Stock |
|
| 2.5KG | RMB319.20 | In Stock |
|
| 5kg | RMB479.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 158-161 °C(lit.) |
| Boiling point: | 211 °C(lit.) |
| bulk density | 400-500kg/m3 |
| Density | 1.44 |
| vapor density | 4.8 (vs air) |
| vapor pressure | 1 mm Hg ( 114 °C) |
| refractive index | 1,565 |
| FEMA | 3985 | 2-HYDROXYBENZOIC ACID |
| Flash point: | 157 °C |
| storage temp. | 2-8°C |
| solubility | ethanol: 1 M at 20 °C, clear, colorless |
| form | Solid |
| pka | 2.98(at 25℃) |
| color | White to off-white |
| Odor | at 100.00 %. faint phenolic nutty |
| PH | 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution); |
| PH Range | Non0 uorescence (2.5) to dark blue 0 uorescence (4.0) |
| Odor Type | nutty |
| biological source | synthetic |
| Water Solubility | 1.8 g/L (20 ºC) |
| λmax | 210nm, 234nm, 303nm |
| Sensitive | Light Sensitive |
| Merck | 14,8332 |
| JECFA Number | 958 |
| Sublimation | 70 ºC |
| BRN | 774890 |
| Henry's Law Constant | 1.3×103 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Stability: | Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light. |
| Major Application | Semiconductors, nanoparticles, photoresists, lubricating oils, UV absorbers, adhesive, leather, cleaner, hair dye, soaps, cosmetics, pain medication, analgesics, antibacterial agent, treatment of dandruff, hyperpigmented skin, tinea pedis, onychomycosis, osteoporosis, beriberi, fungicidal skin disease, autoimmune disease |
| Cosmetics Ingredients Functions | HAIR CONDITIONING ANTI-SEBORRHEIC FRAGRANCE SKIN CONDITIONING PRESERVATIVE KERATOLYTIC |
| InChI | 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) |
| InChIKey | YGSDEFSMJLZEOE-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccccc1O |
| LogP | 2.01 |
| CAS DataBase Reference | 69-72-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 2-hydroxy-(69-72-7) |
| EPA Substance Registry System | Salicylic acid (69-72-7) |
Description and Uses
Salicylic acid (from Latin salix, willow tree, from the bark of which the substance used to be obtained) is a mono hydroxy benzoic acid, a type of phenolic acid and a beta hydroxy acid. This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. It is derived from the metabolism of salicin. In addition to being an important active metabolite of aspirin (acetylsalicylic acid), which acts in part as a prod rug to salicylic acid, it is probably best known for its use in anti-acne treatments. The salts and esters of salicylic acid are known as salicylates.
Salicylic Acid is an Impurity of Acetylsalicylic Acid (A187780). Acetylsalicylic acid Impurity B.
Safety
| Symbol(GHS) |    GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302-H318-H361d |
| Precautionary statements | P202-P264-P280-P301+P312-P305+P351+P338-P308+P313 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn,F |
| Risk Statements | 22-41-36/37/38-36-20/21/22-11 |
| Safety Statements | 26-39-37/39-36-36/37-16 |
| RIDADR | UN 1648 3 / PGII |
| WGK Germany | 1 |
| RTECS | VO0525000 |
| Autoignition Temperature | 500 °C |
| TSCA | TSCA listed |
| HS Code | 29182100 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Repr. 2 |
| Hazardous Substances Data | 69-72-7(Hazardous Substances Data) |
| Toxicity | LD50 i.v. in mice: 500 mg/kg (Sota) |
