A7388912
(S)-Propranolol Hydrochloride , ≥98% , 4199-10-4
Synonym(s):
(S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride
CAS NO.：4199-10-4
Empirical Formula: C16H22ClNO2
Molecular Weight: 295.8
MDL number: MFCD00064547
EINECS: 224-096-0
| Pack Size | Price | Stock | Quantity |
| 100MG | RMB351.20 | In Stock |
|
| 500MG | RMB1495.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 193-195 °C(lit.) |
| storage temp. | 2-8°C |
| solubility | ethanol: 10 mg/mL |
| form | powder |
| color | White to off-white |
| optical activity | [α]25/D 25.5°, c = 1.0 in ethanol(lit.) |
| Water Solubility | Soluble to 100 mM in water |
| BRN | 3574966 |
| InChI | 1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m0./s1 |
| InChIKey | ZMRUPTIKESYGQW-UQKRIMTDSA-N |
| SMILES | Cl[H].CC(C)NC[C@H](O)COc1cccc2ccccc12 |
| CAS DataBase Reference | 4199-10-4(CAS DataBase Reference) |
Description and Uses
(S)-(-)-Propranolol is the active enantiomer of propranolol, a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. It is also a non-specific serotonin receptor antagonist. Propanolol was one of the first β-adrenergic receptor blockers to be widely used in clinical practice for the treatment of hypertension, angina pectoris, and cardiac ischemia.
active enantiomer, 5-HT1 receptor antagonist
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302+H312+H332 |
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 36 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
