7-Ethylcamptothecin , 10mMinDMSO , 78287-27-1

CAS NO.：78287-27-1

Empirical Formula: C22H20N2O4

Molecular Weight: 376.41

MDL number: MFCD06657922

PRODUCT Properties

• Melting point: 236-241°C
• Boiling point: 752.9±60.0 °C(Predicted)
• Density: 1.43
• storage temp.: Sealed in dry,2-8°C
• solubility: Chloroform and Methanol Mixture (Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
• form: Solid
• pka: 11.24±0.20(Predicted)
• color: Pale Yellow to Light Orange
• InChI: InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1
• InChIKey: MYQKIWCVEPUPIL-JOCHJYFZSA-N
• SMILES: N1C2C(=CC=CC=2)C(CC)=C2CN3C(C=12)=CC1[C@](CC)(O)C(=O)OCC=1C3=O
• CAS DataBase Reference: 78287-27-1(CAS DataBase Reference)

Description and Uses

7-Ethylcamptothecin is used as an anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301+H311+H331
• Precautionary statements: P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P403+P233-P405-P501
• Risk Statements: 23/34/35
• Safety Statements: 3/14-6-36/37/39
• RIDADR: 1544
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29349990