A7656758
GSK-2881078 , 10mMinDMSO , 1539314-06-1
CAS NO.：1539314-06-1
Empirical Formula: C14H13F3N2O2S
Molecular Weight: 330.33
MDL number:
EINECS: 1539314-060-1
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 521.6±50.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | ≤20mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide |
| form | crystalline solid |
| color | White to off-white |
| InChI | InChI=1S/C14H13F3N2O2S/c1-9(8-22(2,20)21)19-6-5-11-12(19)4-3-10(7-18)13(11)14(15,16)17/h3-6,9H,8H2,1-2H3/t9-/m1/s1 |
| InChIKey | SKDVMPZQJMZEAC-SECBINFHSA-N |
| SMILES | N1([C@H](C)CS(C)(=O)=O)C2=C(C(C(F)(F)F)=C(C#N)C=C2)C=C1 |
Description and Uses
GSK2881078 is a selective androgen receptor modulator (SARM). It induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM), an effect that can be inhibited by the non-steroidal AR antagonist bicalutamide .
GSK 2881078 is a selective androgen receptor modulator which can display agonistic properties in anabolic target tissues
Safety
| Symbol(GHS) |   GHS08,GHS06 |
| Signal word | Danger |
| Hazard statements | H301-H360 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
