Terpineol , 95%, the heterogeneous mixture , 8000-41-7

CAS NO.：8000-41-7

Empirical Formula: C10H18O

Molecular Weight: 154.25

MDL number: MFCD00001557

EINECS: 232-268-1

PRODUCT Properties

• Melting point: 18°C
• Boiling point: 213-218 °C (lit.)
• Density: 0.934 g/mL at 20 °C (lit.)
• vapor pressure: 3 hPa (20 °C)
• refractive index: 1.481-1.486
• Flash point: 95°C
• storage temp.: Store below +30°C.
• solubility: ethanol: soluble1.25ml/10ml, clear to slightly hazy, colorless to light yellow (50% ethanol)
• form: Liquid
• color: Clear colorless to slightly yellow
• Odor: at 100.00 %. fresh clean woody pine floral lime
• Odor Type: herbal
• biological source: synthetic
• Water Solubility: slightly
• FreezingPoint: 2℃
• Dielectric constant: 2.8（20℃）
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong acids.
• Cosmetics Ingredients Functions: FRAGRANCE; PERFUMING
• InChIKey: WUOACPNHFRMFPN-UHFFFAOYSA-N
• LogP: 3.330 (est)
• CAS DataBase Reference: 8000-41-7(CAS DataBase Reference)
• EPA Substance Registry System: Terpineol (8000-41-7)

Description and Uses

Terpineol is a monoterpene alcohol that has been found in a variety of plants, including Cannabis, and has diverse biological activities. Terpineol contains the four isomers α-, β-, and γ-terpineol and terpinen-4-ol. α-Terpineol has antibacterial and antinociceptive properties. It is active against a variety of periodontopathic and cariogenic bacteria, including strains of P. gingivalis, F. nucleatum, and A. actinomycetemcomitans (MICs = 0.1-0.8 mg/ml), however, it is toxic to KB cells when used at a concentration of 0.8 mg/ml. It also reduces mechanical hyperalgesia, as well as spontaneous and palpation-induced nociception, in a mouse model of cancer-induced pain beginning on day 5 when administered at a dose of 50 mg/kg per day. Terpinen-4-ol has anticonvulsant properties, inhibiting pentylenetetrazol-induced seizures in mice when used at doses ranging from 50 to 200 mg/kg. α-Terpineol and terpinen-4-ol also have anti-inflammatory properties, reducing LPS-induced production of IL-1β, IL-6, and IL-10, but not TNF-α, in U937 cells. This product is a mixture of α-, β-, and γ-terpineol.

Solvent for hydrocarbon materials, mutual solvent for resins and cellulose esters and ethers, perfumes, soaps, disinfectant, antioxidant, flavoring agent.

Safety

• Symbol(GHS): GHS07
• Symbol(GHS): GHS07
• Signal word: Warning
• Signal word: Warning
• Hazard statements: H315-H319
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
• Precautionary statements: P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
• Hazard Codes: Xi
• Risk Statements: 38-36/37/38-36/38-37/38
• Safety Statements: 37-36-26-24/25
• WGK Germany: 2
• RTECS: WZ6600000
• TSCA: Yes
• HS Code: 29061990
• Toxicity: LD50 orally in Rabbit: 4300 mg/kg