NG-Monomethyl-L-arginineAcetate , 10mMinWater , 53308-83-1

Synonym(s):
N_ω-Methyl-L-arginine acetate salt;L-NMMA;N ^ω-Me-L-Arg, N ^G-Me-L-Arg, AcOH, L-NMMA;N^ω-Me-L-Arg, N^G-Me-L-Arg, AcOH, L-NMMA;N⁵-(Methylamidino)-L-ornithine acetate salt

CAS NO.：53308-83-1

Empirical Formula: C9H20N4O4

Molecular Weight: 248.28

MDL number: MFCD00069311

PRODUCT Properties

• Melting point: 180-190 °C
• alpha: D22 +9.5° (c = 0.10 in water)
• Boiling point: 391.35°C (rough estimate)
• Density: 1.2162 (rough estimate)
• refractive index: 1.6300 (estimate)
• storage temp.: 2-8°C
• solubility: H₂O: 1 mg/mL, clear, colorless
• form: Powder
• color: White to Off-white
• Water Solubility: Soluble in water (50 mM)
• BRN: 6674255
• Stability: Store at - 5°C; Desiccate Recommended
• InChI: 1S/C7H16N4O2.C2H4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13;1-2(3)4/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11);1H3,(H,3,4)/t5-;/m0./s1
• InChIKey: IKPNWIGTWUZCKM-JEDNCBNOSA-N
• SMILES: CC(O)=O.CNC(=N)NCCC[C@H](N)C(O)=O

Description and Uses

L-NMMA is the archetypal competitive NOS inhibitor to which other inhibitors are often compared. It is a relatively non-selective inhibitor of all NOS isoforms. The K_i values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively.

Nitric oxide synthase inhibitor

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• Safety Statements: 22-24/25
• WGK Germany: 3
• HS Code: 29252900
• Storage Class: 11 - Combustible Solids