2,2,2-Trifluoroacetophenone , ≥98.0%(GC) , 434-45-7

Synonym(s):
α,α,α-Trifluoroacetophenone;Phenyl trifluoromethyl ketone

CAS NO.：434-45-7

Empirical Formula: C8H5F3O

Molecular Weight: 174.12

MDL number: MFCD00000420

EINECS: 207-103-1

PRODUCT Properties

• Melting point: -40 °C
• Boiling point: 166 °C
• Density: 1.28
• refractive index: 1.46
• Flash point: 41 °C
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform, Ethyl Acetate
• form: clear liquid
• color: Colorless to Light yellow to Light orange
• Specific Gravity: 1.240
• Water Solubility: PRACTICALLY INSOLUBLE
• BRN: 1866286
• InChI: 1S/C8H5F3O/c9-8(10,11)7(12)6-4-2-1-3-5-6/h1-5H
• InChIKey: KZJRKRQSDZGHEC-UHFFFAOYSA-N
• SMILES: FC(F)(F)C(=O)c1ccccc1
• CAS DataBase Reference: 434-45-7(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2,2,2-trifluoro-1-phenyl-(434-45-7)
• EPA Substance Registry System: Ethanone, 2,2,2-trifluoro-1-phenyl- (434-45-7)

Description and Uses

2,2,2-Trifluoroacetophenone is a fluorinated acetophenone with inhibitory activity of acetylcholinesterase. 2,2,2-Trifluoroacetophenone was shown to have neuroprotective activity by inhibiting apoptosis in cerebellar granule neurons.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Warning
• Hazard statements: H226-H315-H319-H335
• Precautionary statements: P210-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
• Hazard Codes: Xi,F
• Risk Statements: 10-36/37/38
• Safety Statements: 26-36-37/39-16
• RIDADR: UN 1224 3/PG 3
• WGK Germany: 3
• Hazard Note: Corrosive/Lachrymatory
• TSCA: TSCA listed
• HazardClass: 3
• PackingGroup: III
• HS Code: 29147090
• Storage Class: 3 - Flammable liquids
• Hazard Classifications: Eye Irrit. 2; Flam. Liq. 3; Skin Irrit. 2; STOT SE 3
• Limited Quantities: 1.0 L (0.3 gallon) (liquid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)