A7695412
Trimethyl orthoacetate , 98% , 1445-45-0
Synonym(s):
1,1,1-Trimethoxyethane;1,1,1-Trimethoxyethane, Orthoacetic acid trimethyl ester;Trimethyl orthoacetate
CAS NO.：1445-45-0
Empirical Formula: C5H12O3
Molecular Weight: 120.15
MDL number: MFCD00008477
EINECS: 215-892-9
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 107-109 °C(lit.) |
| Density | 0.944 g/mL at 25 °C(lit.) |
| vapor pressure | 20 hPa (20 °C) |
| refractive index | n |
| Flash point: | 62 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless to slightly brown |
| Specific Gravity | 0.960 (20/4℃) |
| Water Solubility | HYDROLYSIS |
| Sensitive | Moisture Sensitive |
| BRN | 1098338 |
| InChIKey | HDPNBNXLBDFELL-UHFFFAOYSA-N |
| LogP | 1.13 at 25℃ |
| CAS DataBase Reference | 1445-45-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethane, 1,1,1-trimethoxy-(1445-45-0) |
| EPA Substance Registry System | Trimethyl orthoacetate (1445-45-0) |
Description and Uses
Trimethyl orthoacetate has been used in the preparation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines.
Safety
| Symbol(GHS) |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225-H317-H319 |
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 |
| Hazard Codes | F,Xi |
| Risk Statements | 11-43-38-36/37/38 |
| Safety Statements | 16-37/39-24-33-26-7/9 |
| RIDADR | UN 3272 3/PG 2 |
| WGK Germany | 1 |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29159080 |
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
