3-MaleimidopropionicAcid , 10mMinDMSO , 7423-55-4

Synonym(s):
N-(2-Carboxyethyl)maleimide;3-Maleimidopropionic acid

CAS NO.：7423-55-4

Empirical Formula: C7H7NO4

Molecular Weight: 169.13

MDL number: MFCD00043030

EINECS: 616-069-0

PRODUCT Properties

• Melting point: 103-106 °C (lit.)
• Boiling point: 382.5±25.0 °C(Predicted)
• Density: 1.473±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 4.18±0.10(Predicted)
• form: Solid
• color: White
• Water Solubility: Soluble in methanol, dimethyl formamide, alcohol and dimethyl sulfoxide. Slightly soluble in water.
• Sensitive: Moisture Sensitive
• BRN: 1528952
• InChI: InChI=1S/C7H7NO4/c9-5-1-2-6(10)8(5)4-3-7(11)12/h1-2H,3-4H2,(H,11,12)
• InChIKey: IUTPJBLLJJNPAJ-UHFFFAOYSA-N
• SMILES: N1(CCC(O)=O)C(=O)C=CC1=O
• CAS DataBase Reference: 7423-55-4(CAS DataBase Reference)

Description and Uses

3-Maleimidopropionic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

3-Maleimidopropionic acid is a sulfhydryl reactive heterobifunctional crosslinking reagent.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• HS Code: 29252900
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3