Navoximod , 10mMinDMSO , 1402837-78-8

CAS NO.：1402837-78-8

Empirical Formula: C18H21FN2O2

Molecular Weight: 316.38

MDL number: MFCD29472253

PRODUCT Properties

• Boiling point: 555.4±35.0 °C(Predicted)
• Density: 1.42±0.1 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMSO:100.0(Max Conc. mg/mL);316.09(Max Conc. mM)
• pka: 14.66±0.20(Predicted)
• form: Solid
• color: White to light yellow
• InChI: InChI=1/C18H21FN2O2/c19-14-3-1-2-13-16-9-20-10-21(16)15(18(13)14)8-17(23)11-4-6-12(22)7-5-11/h1-3,9-12,15,17,22-23H,4-8H2/t11-,12-,15-,17+/s3
• InChIKey: YGACXVRLDHEXKY-YYJRJVKZNA-N
• SMILES: C([C@@H]1N2C=NC=C2C2=CC=CC(F)=C12)[C@H]([C@]1([H])CC[C@@H](O)CC1)O |&1:1,14,15,19,r|

Description and Uses

Navoximod (GDC-0919; NLG-?919) is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM.