3,4',5-Trimethoxy-trans-stilbene , 97% , 22255-22-7
Synonym(s):
1,3-dimethoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene; Tri-O-methylresveratrol; Trimethoxy-trans-stilbene
CAS NO.：22255-22-7
Empirical Formula: C17H18O3
Molecular Weight: 270.32
MDL number: MFCD02093500
EINECS: 694-659-7
| Pack Size | Price | Stock | Quantity |
| 1G | RMB66.40 | In Stock |
|
| 5G | RMB212.00 | In Stock |
|
| 25g | RMB696.00 | In Stock |
|
| 100g | RMB1740.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 57°C |
| Boiling point: | 423.8±35.0 °C(Predicted) |
| Density | 1.104±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: ≥34mg/mL |
| form | powder to crystal |
| color | white to tan |
| InChI | InChI=1S/C17H18O3/c1-18-15-8-6-13(7-9-15)4-5-14-10-16(19-2)12-17(11-14)20-3/h4-12H,1-3H3/b5-4+ |
| InChIKey | GDHNBPHYVRHYCC-SNAWJCMRSA-N |
| SMILES | C1(OC)=CC(/C=C/C2=CC=C(OC)C=C2)=CC(OC)=C1 |
| CAS DataBase Reference | 22255-22-7 |
Description and Uses
trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively). trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM.
Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. When the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers, the inhibition of cell growth and pro-apoptotic activities of resveratrol are enhanced.
Safety
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H315-H318-H335-H410 |
| Precautionary statements | P261-P264-P273-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi,N |
| Risk Statements | 36/37/38-50/53-41-37/38 |
| Safety Statements | 26-36/37/39-61-60-39 |
| RIDADR | UN 3077 9 / PGIII |
| HS Code | 2909.30.6000 |
