A7707912
Thiophene , 99% , 110-02-1
Synonym(s):
Thiophene;CYP3A;Thiofuran;Thiole;HLP
CAS NO.：110-02-1
Empirical Formula: C4H4S
Molecular Weight: 84.14
MDL number: MFCD00005413
EINECS: 203-729-4
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | -38 °C (lit.) |
| Boiling point: | 84 °C (lit.) |
| Density | 1.051 g/mL at 25 °C (lit.) |
| vapor density | 2.9 (vs air) |
| vapor pressure | 40 mm Hg ( 12.5 °C) |
| refractive index | n |
| Flash point: | -9 °C |
| storage temp. | Store below +30°C. |
| solubility | Miscible with carbon tetrachloride, heptane, pyrimidine, dioxane, toluene, and many organic
solvents (quoted, Keith and Walters, 1992) |
| form | powder |
| color | Clear |
| Specific Gravity | 1.06 |
| Odor | at 0.10 % in propylene glycol. alliaceous garlic |
| Odor Type | sulfurous |
| biological source | mouse |
| explosive limit | 1.5-12.5%(V) |
| Odor Threshold | 0.00056ppm |
| Water Solubility | INSOLUBLE |
| Merck | 14,9353 |
| BRN | 103222 |
| Henry's Law Constant | 2.33 and 2.70 in distilled water and seawater, respectively (Przyjazny et al., 1983) |
| Dielectric constant | 9.3（20℃） |
| Stability: | Stable. Highly flammable. Incompatible with strong oxidizing agents, nitrates. |
| LogP | 1.81-1.86 at pH10 |
| Surface tension | 26.13mN/m at 298.15K |
| CAS DataBase Reference | 110-02-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Thiophene(110-02-1) |
| EPA Substance Registry System | Thiophene (110-02-1) |
Description and Uses
Thiophene is an important building block in dyes, agrochemicals and pharmaceuticals synthesis. It is involved in the chloroalkylation reactions in 2,5-positions. It is also used to prepare butane by reduction with raney nickel, 2-vinylthiophene, dithienyl, and 2-halo thiophenes by reacting with halogens.
Safety
| Symbol(GHS) |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225-H302-H319-H340-H350-H412 |
| Precautionary statements | P202-P210-P273-P301+P312-P305+P351+P338-P308+P313 |
| Hazard Codes | F,Xn,Xi,T |
| Risk Statements | 45-46-11-20/21/22-41-52/53-36-20/22-37/38-22-48/20/21/22 |
| Safety Statements | 53-26-39-45-61-36/37/39-16-36 |
| RIDADR | UN 2414 3/PG 2 |
| WGK Germany | 3 |
| RTECS | XM7350000 |
| Autoignition Temperature | 743 °F |
| Hazard Note | Irritant/Highly Flammable |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29349990 |
| Hazardous Substances Data | 110-02-1(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 1400 mg/kg |
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
