A7717312
2,2,2-Trifluoroethanol , NMRgrade,≥99.8% , 75-89-8
Synonym(s):
2,2,2-Trifluoroethanol;TFEA;transcription factor binding to IGHM enhancer 3;Transcription factor for IgH enhancer;Trifluoroethyl alcohol
CAS NO.:75-89-8
Empirical Formula: C2H3F3O
Molecular Weight: 100.04
MDL number: MFCD00004672
EINECS: 200-913-6
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | −44 °C(lit.) |
| Boiling point: | 77-80 °C(lit.) |
| Density | 1.391 g/mL at 20 °C |
| vapor density | 3.5 (vs air) |
| vapor pressure | 70 mm Hg ( 25 °C) |
| refractive index | n |
| Flash point: | 85 °F |
| storage temp. | Store below +30°C. |
| solubility | soluble in Chloroform, Methanol |
| pka | 12.4(at 25℃) |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 1.373 |
| Odor | Alcoholic odour |
| PH Range | 5-7 (10% aq soln) |
| PH | 7 |
| biological source | goat |
| explosive limit | 8.4-28.8%(V) |
| Water Solubility | Miscible with water, ethers, ketones, alcohols and chloroform. |
| λmax | λ: 260 nm Amax: ≤0.03 λ: 280 nm Amax: ≤0.02 |
| Merck | 14,9682 |
| BRN | 1733203 |
| Dielectric constant | 8.5500000000000007 |
| Stability: | Stable. Flammable - note wide explosion limits. Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, sodium, potassium. |
| InChIKey | RHQDFWAXVIIEBN-UHFFFAOYSA-N |
| CAS DataBase Reference | 75-89-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanol, 2,2,2-trifluoro-(75-89-8) |
| EPA Substance Registry System | 2,2,2-Trifluoroethanol (75-89-8) |
Description and Uses
2,2,2-Trifluoroethanol (Trifluoroethyl alcohol, TFE) is used to study the conformational states of proteins and the folding refolding processes of proteins.
Safety
| Symbol(GHS) | ![]() ![]() ![]() ![]() GHS02,GHS05,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H226-H301+H331-H318-H360F-H373 |
| Precautionary statements | P201-P210-P280-P301+P310-P304+P340+P311-P305+P351+P338 |
| Hazard Codes | Xn,T,F |
| Risk Statements | 10-20/21/22-37/38-41-62-38-36/37/38 |
| Safety Statements | 26-36-39-45-36/37/39-16 |
| RIDADR | UN 1986 3/PG 3 |
| WGK Germany | 1 |
| RTECS | KM5250000 |
| Autoignition Temperature | ~896 °F |
| Hazard Note | Flammable/Toxic |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29055910 |
| Toxicity | LD50 orally in Rabbit: 240 mg/kg LD50 dermal Rat 1680 mg/kg |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |






