PrazosinHydrochloride , 2mMinDMSO , 19237-84-4

Synonym(s):
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride;Furazosin hydrochloride;Prazosin HCl;Prazosin hydrochloride

CAS NO.：19237-84-4

Empirical Formula: C19H22ClN5O4

Molecular Weight: 419.86

MDL number: MFCD00058177

EINECS: 242-903-4

PRODUCT Properties

• Melting point: 277 - 280 °C
• storage temp.: 2-8°C
• solubility: H₂O: 1 mg/mL, clear, colorless
• form: solid
• color: white
• Water Solubility: Soluble in dimethyl sulfoxide, ethanol, water, methanol.
• Merck: 14,7717
• BRN: 4303561
• InChI: InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H
• InChIKey: WFXFYZULCQKPIP-UHFFFAOYSA-N
• SMILES: N1(C2=NC(N)=C3C(=N2)C=C(OC)C(OC)=C3)CCN(C(C2=CC=CO2)=O)CC1.[H]Cl
• CAS DataBase Reference: 19237-84-4(CAS DataBase Reference)

Description and Uses

Prazosin Hydrochloride (Terazosin EP Impurity K) is an antihypertensive. α1-Adrenergic blocker.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335-H361
• Precautionary statements: P201-P301+P312+P330-P302+P352-P305+P351+P338-P308+P313
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38-62
• Safety Statements: 28-36
• RIDADR: 3249
• WGK Germany: 3
• RTECS: VA1350000
• F: 10
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 2934990002
• Hazardous Substances Data: 19237-84-4(Hazardous Substances Data)
• Toxicity: dog,LD50,oral,> 700mg/kg (700mg/kg),GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSKIDNEY, URETER, AND BLADDER: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING,Oyo Yakuri. Pharmacometrics. Vol. 17, Pg. 39, 1979.