4-(Trimethylsilyl)-3-butyn-2-one , 97% , 5930-98-3

CAS NO.：5930-98-3

Empirical Formula: C7H12OSi

Molecular Weight: 140.26

MDL number: MFCD00190212

EINECS: 628-294-1

PRODUCT Properties

• Melting point: 99 °C
• Boiling point: 156 °C(lit.)
• Density: 0.854 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.442(lit.)
• Flash point: 83 °F
• storage temp.: Flammables area
• form: clear liquid
• color: Colorless to Light yellow to Light orange
• Specific Gravity: 0.854
• Hydrolytic Sensitivity: 4: no reaction with water under neutral conditions
• InChI: InChI=1S/C7H12OSi/c1-7(8)5-6-9(2,3)4/h1-4H3
• InChIKey: NQEZDDPEJMKMOS-UHFFFAOYSA-N
• SMILES: CC(=O)C#C[Si](C)(C)C
• CAS DataBase Reference: 5930-98-3(CAS DataBase Reference)

Description and Uses

4-(Trimethylsilyl)-3-butyn-2-one (TMSB) has been used to investigate its asymmetric bioreduction to (S)-4-(trimethylsilyl)-3-butyn-2-ol {(S)-TMSBOL} by employing biocompatible water-immiscible ionic liquids (ILs). TMSB may be used for the synthesis of entecavir (BMS-200475).

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Warning
• Hazard statements: H226-H315-H319-H335
• Precautionary statements: P210-P233-P240-P241-P303+P361+P353-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 10-36/37/38
• Safety Statements: 16-26-36-37/39
• RIDADR: UN 1224 3/PG 3
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• HS Code: 29319090
• Limited Quantities: 5.0 L (1.3 gallons) (liquid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)