Piperlongumine , 10mMinDMSO , 20069-09-4

Synonym(s):
5,6-Dihydro-1-(1-oxo-3-[3,4,5-trimethoxyphenyl]-trans-2-propenyl)-2[1H]-pyridinone;5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-Pyridinone;Piplartin;Piplartine;Piplartine, (E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one

CAS NO.：20069-09-4

Empirical Formula: C17H19NO5

Molecular Weight: 317.34

MDL number: MFCD00075706

PRODUCT Properties

• Melting point: 124°C
• Boiling point: 475.6±45.0 °C(Predicted)
• Density: 1.223±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO: ≥5mg/mL at warmed to 60°C
• pka: -1.88±0.20(Predicted)
• form: powder
• color: white to beige
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
• Cosmetics Ingredients Functions: SKIN CONDITIONING - MISCELLANEOUS; ANTIOXIDANT; BLEACHING
• InChI: InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6-15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+
• InChIKey: VABYUUZNAVQNPG-BQYQJAHWSA-N
• SMILES: C1(=O)N(C(=O)/C=C/C2=CC(OC)=C(OC)C(OC)=C2)CCC=C1
• LogP: 2.340 (est)

Description and Uses

A piperidinone alkaloid present in Piper longum, the structure has been shown to be N-(3:4:5-trimethoxycinnamoyl)-Lls-piperidin-2-one. In the plant, the base occurs mainly in the roots.

anti-asthma, antibronchitis

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H320-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• WGK Germany: 3
• RTECS: UU7785850
• HS Code: 2932209090