Tenoxicam , ≥98% , 59804-37-4

Synonym(s):
4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide

CAS NO.：59804-37-4

Empirical Formula: C13H11N3O4S2

Molecular Weight: 337.37

MDL number: MFCD00083502

EINECS: 620-500-8

PRODUCT Properties

• Melting point: 209-2130C (dec)
• Density: 1.4737 (rough estimate)
• refractive index: 1.6390 (estimate)
• storage temp.: 2-8°C
• solubility: Practically insoluble in water, sparingly soluble in methylene chloride, very slightly soluble in anhydrous ethanol. It dissolves in solutions of acids and alkalis.
• pka: pKa1 5.3, pKa2 1.1(at 25℃)
• form: Solid
• color: White to Yellow to Green
• Water Solubility: 61.9mg/L(32 ºC)
• InChI: InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18)
• InChIKey: LZNWYQJJBLGYLT-UHFFFAOYSA-N
• SMILES: S1(=O)(=O)C2C=CSC=2C(O)=C(C(NC2=NC=CC=C2)=O)N1C
• CAS DataBase Reference: 59804-37-4

Description and Uses

Tenoxicam is a non-steroidal antiinflammatory agent with a profile similar to related piroxicam and now withdrawn isoxicam (55). It is useful in the treatment of rheumatoid arthritis, osteoarthritis and related disorders.

Tenoxicam has been used:
    as a non-steroidal anti-inflammatory agent (NSAID) to study its effects on root gravitropism in Arabidopsis thaliana
    as a standard in microanalysis of NSAIDs by spectrophotometry
    to test its effect on surface potential andmembrane fluidity modification in phosphoglyceride monolayers

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301+H311+H331
• Precautionary statements: P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
• Hazard Codes: T,Xi
• Risk Statements: 23/24/25-36/37/38
• Safety Statements: 36/37/39-45-36-26-36/37
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 2
• RTECS: XJ9095060
• HS Code: 2934.99.3000
• HazardClass: 6.1