1,1,3-Trichloroacetone , >80.0%(GC) , 921-03-9

Synonym(s):
1,1,3-Trichloro-2-propanone;TCA

CAS NO.：921-03-9

Empirical Formula: C3H3Cl3O

Molecular Weight: 161.41

MDL number: MFCD00040500

EINECS: 213-063-6

PRODUCT Properties

• Melting point: 9-11 °C(lit.)
• Boiling point: 88-90 °C76 mm Hg(lit.)
• Density: 1.512 g/mL at 20 °C(lit.)
• vapor pressure: 30-350Pa at 20-50℃
• refractive index: n20/D 1.491
• Flash point: 80
• storage temp.: Refrigerator, under inert atmosphere
• solubility: Chloroform, Methanol
• form: Oil
• color: Clear Colourless
• BRN: 1746647
• InChIKey: ZWILTCXCTVMANU-UHFFFAOYSA-N
• LogP: 0.45
• CAS DataBase Reference: 921-03-9(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanone, 1,1,3-trichloro-(921-03-9)

Description and Uses

1,1,3-Trichloroacetone is direct-acting mutagens in the Ames/Salmonella assay. It is precursor for the generation of 1,3-dihalo oxyallyl intermediates, which undergo [4 + 3] cycloadditions with a host of 1,3-diene systems.

1,1,3-Trichloroacetone is a reagent used to synthesize chlorinated 5-hydroxy-4-methyl-2(5H)-furanones and mucochloric acid. In addition, it can also be used to synthesize (+)-Phorbol. Phorbol derivatives are important for biomedical research and capable of stimulating T-cell activation, proliferation and cytokine production.

Safety

• Symbol(GHS): GHS05,GHS06,GHS09
• Signal word: Danger
• Hazard statements: H301+H311-H314-H330-H410
• Precautionary statements: P273-P280-P301+P310+P330-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310
• Hazard Codes: T+,N
• Risk Statements: 25-26-34-50/53-68-21
• Safety Statements: 26-36/37/39-45-60-61-28
• RIDADR: UN 3390 6.1/PG 1
• WGK Germany: 3
• RTECS: UC3840000
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 29147000
• Toxicity: mmo-sat 50 mL/plate ENMUDM 7,163,85