4-(Trifluoromethyl)-<I>N</I>-methylaniline , 97% , 22864-65-9

CAS NO.：22864-65-9

Empirical Formula: C8H8F3N

Molecular Weight: 175.15

MDL number: MFCD07369717

EINECS: 245-739-1

PRODUCT Properties

• Boiling point: 105-106 °C/20 mmHg (lit.)
• Density: 1.2394 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.4888(lit.)
• Flash point: 210 °F
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• pka: 2.58±0.12(Predicted)
• form: clear liquid
• color: Colorless to Light orange to Yellow
• InChIKey: UTUYWZJPVLDHJJ-UHFFFAOYSA-N

Description and Uses

4-(Trifluoromethyl)-N-methylaniline is used in the synthesis of Tasquinimod (T007820), an orally active antiangiogenic agent which may inhibit HDAC4 signalling. This affects cancer cell survival thus making this compound and anti-cancer agent.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H317
• Precautionary statements: P280-P301+P312+P330-P302+P352
• Hazard Codes: Xn
• Risk Statements: 22-43
• Safety Statements: 36/37
• WGK Germany: 3
• HS Code: 2921430090