Vinylmagnesium bromide solution , 1.0MinTHF , 1826-67-1

CAS NO.：1826-67-1

Empirical Formula: C2H3BrMg

Molecular Weight: 131.26

MDL number: MFCD00000042

EINECS: 217-375-3

PRODUCT Properties

• Density: 0.981 g/mL at 25 °C
• Flash point: 1 °F
• storage temp.: Refrigerator
• solubility: vigorous reaction
• form: Solution
• color: Clear light brown to brown
• Water Solubility: vigorous reaction
• BRN: 3535841
• InChI: InChI=1S/C2H3.BrH.Mg/c1-2;;/h1H,2H2;1H;/q;;+1/p-1
• InChIKey: XHHHAXOHMKAOSL-UHFFFAOYSA-M
• SMILES: C(=C)[Mg]Br
• CAS DataBase Reference: 1826-67-1(CAS DataBase Reference)
• EPA Substance Registry System: Magnesium, bromoethenyl- (1826-67-1)

Description and Uses

Vinylmagnesium bromide solution (1 M in THF) may be used in the synthesis of 2-vinylchroman-4-ones by the conjugate addition with chromones in the presence of a Lewis acid.
It may also be used in the following transformations:

• (S)-3-(benzyloxy)-4-oxo-butanoic acid methyl ester to methyl (3S,4S)-4-hydroxy-3-(phenylmethoxy)hex-5-enoate.
• (R)-1-Azido-5,6-epoxyhexane to (S)-1-(4-azidobutyl)-2-propen-1-ol.
• 2,3-O-Isopropylidene-D-ribose to 1-[(4R,5S)-5-((1S)-1-hydroxyallyl)-2,2-dimethyl[1,3]dioxolan-4-yl]ethane-1,2-diol.
• (4S,5S)-2,2-Dimethyl-5-vinyl[1,3]dioxolane-4-carbaldehyde to (1R,4R,5S)- and (1S,4R,5S)-1-(2,2-dimethyl-5-vinyl[1,3]dioxolan-4-yl)prop-2-en-1-ol.
• Ethyl levulinate to ?-methyl-?-vinylbutyrolactone.

Safety

• Symbol(GHS): GHS02,GHS05,GHS07,GHS08
• Signal word: Danger
• Hazard statements: H225-H260-H302-H314-H335-H351
• Precautionary statements: P210-P231+P232-P280-P370+P378-P402+P404-P403+P235
• Hazard Codes: F,C
• Risk Statements: 11-14-19-34-14/15-40-37
• Safety Statements: 16-26-29-33-36/37/39-45-6A-43B-43
• RIDADR: UN 3399 4.3/PG 2
• WGK Germany: 1
• F: 1-3-10
• HazardClass: 4.3/3
• PackingGroup: I
• HS Code: 29319090
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)