Z-D-Pro-OH , 98% , 6404-31-5

CAS NO.：6404-31-5

Empirical Formula: C13H15NO4

Molecular Weight: 249.26

MDL number: MFCD00063228

EINECS: 229-021-5

PRODUCT Properties

• Melting point: 76-78 °C(lit.)
• alpha: 40 º (c=2, EtOH)
• Boiling point: 432.3±45.0 °C(Predicted)
• Density: 1.309±0.06 g/cm3(Predicted)
• refractive index: 40 ° (C=2, EtOH)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• form: Crystalline Powder or Powder
• pka: 3.99±0.20(Predicted)
• color: White
• optical activity: [α]25/D +40.2°, c = 2 in ethanol
• BRN: 485188
• InChI: InChI=1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m1/s1
• InChIKey: JXGVXCZADZNAMJ-LLVKDONJSA-N
• SMILES: N1(C(OCC2=CC=CC=C2)=O)CCC[C@@H]1C(O)=O
• CAS DataBase Reference: 6404-31-5(CAS DataBase Reference)

Description and Uses

N-(Benzyloxycarbonyl)-D-proline is an an N-Cbz-protected form of D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H335-H319-H302-H315-H332
• Precautionary statements: P264-P280-P305+P351+P338-P337+P313P-P261-P271-P304+P340-P312-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• HS Code: 29339900