N-Heptafluorobutyrylimidazole , Used for GC derivatives , 32477-35-3

Synonym(s):
1-(Perfluorobutyryl)imidazole;NSC 151966

CAS NO.：32477-35-3

Empirical Formula: C7H3F7N2O

Molecular Weight: 264.1

MDL number: MFCD00014503

EINECS: 251-063-8

PRODUCT Properties

• Melting point: 9-13 °C
• Boiling point: 161 °C(lit.)
• Density: 1.490 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.3865(lit.)
• Flash point: 171 °F
• storage temp.: 2-8°C
• solubility: Miscible with chloroform and methanol.
• form: Oil
• pka: 1.37±0.10(Predicted)
• color: Pale Yellow
• Sensitive: Hygroscopic
• BRN: 4488026
• Stability: Moisture Sensitive
• InChIKey: MSYHGYDAVLDKCE-UHFFFAOYSA-N
• CAS DataBase Reference: 32477-35-3(CAS DataBase Reference)
• NIST Chemistry Reference: N-Heptafluorobutyrylimidazole(32477-35-3)
• EPA Substance Registry System: 1-(Heptafluorobutyryl)imidazole (32477-35-3)

Description and Uses

1-(Heptafluorobutyryl)imidazole is used in gas chromatography for the determination of various pharmaceutical compounds like retronecine in biological matrixes. It acts as a reagent for derivatize amine-groups. It plays an essential role to reduce GC column degradation due to its non-acidic property. It is an acylating agent, which converts thermally unstable compounds to its more volatile derivative and then made suitable for GC analysis.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H227-H315-H319-H335
• Precautionary statements: P210e-P261-P280a-P305+P351+P338-P405-P501a-P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• F: 3-10-21
• Hazard Note: Irritant/Hygroscopic/Keep Cold
• HazardClass: IRRITANT, MOISTURE SENSITIVE, KEEP COLD
• HS Code: 29332900